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Schizophr Res. 2000 Dec 15;46(2-3):203-7.

IQ scores of treatment-resistant schizophrenia patients before and after the onset of the illness.

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  • 1Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA.


In this study we examined the correlations of actual pre-morbid IQ scores (obtained from routine educational assessments) and estimated current IQ scores in 27 treatment-resistant schizophrenia patients. Pre-morbid (mean = 93) and current (mean = 83) IQ scores were significantly correlated (r = 0.807, P < 0.0001), while duration of illness (10-40 years) was unrelated to the magnitude of IQ score decline (r = -0.103, P = 0.575). These data suggest that pre-morbid IQ test scores are highly predictive of post-morbid scores.

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