Format

Send to

Choose Destination
See comment in PubMed Commons below
Magn Reson Imaging. 2000 Nov;18(9):1151-8.

Evaluation of algorithms for analysis of NMR relaxation decay curves.

Author information

  • 1Laboratory of Molecular Physics, Department of Biomolecular Sciences, Wageningen University, Dreijenlaan 3, 6703 HA, Wageningen, The Netherlands.

Abstract

Quantitative processing of NMR relaxation images depends on the characteristics of the used fitting algorithm. Therefore several common fitting algorithms are compared for decay curves with low signal-to-noise ratios. The use of magnitude data yields a non-zero base line, and is shown to result in an overestimation of the decay time. A simple base line correction is no solution since this yields an equally large underestimation due to overcorrection of the first part of the curve. The use of squared data does yield reliable results, but only in the case of monoexponential decays. The best fitting algorithm under all experimentally occurring conditions turns out to be using real data after phase correction. A phase correction scheme is proposed, which applies to all imaging experiments for which the phase of the pixels is constant over the echo train. This scheme is validated for a phantom and for a tulip bulb.

PMID:
11118770
[PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Other Literature Sources

PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk