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Acta Haematol. 2000;104(1):50-1.

Hydroxyurea as a cause of drug fever.

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  • 1Lin Medical Center, Hematology Clinic, Kupat Holim Clalit, Haifa, Israel.


We report on a patient with essential thrombocythemia treated with hydroxyurea who became febrile 3 weeks after the treatment was started. After drug withdrawal, the fever resolved but after rechallenge there was recurrence of the fever. Although hydroxyurea-induced fever is rare, this drug must be added to the list of drugs that produce fever and the physicians should be aware of this possibility.

Copyright 2000 S. Karger AG, Basel

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