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Australas J Dermatol. 2000 Nov;41(4):257-9.

Erythema multiforme: a case with unusual histopathological features.

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  • 1Royal Brisbane Hospital, Queensland, Australia.


A 14-year-old boy presented with widespread cutaneous and mucosal lesions clinically consistent with erythema multiforme. He gave a history of previous episodes of a similar eruption. Histological examination of a representative lesion showed changes consistent with erythema multiforme. It also, however, contained large numbers of eosinophils, forming a dermal interstitial infiltrate and epidermal microabscesses. The full blood examination showed a persistent eosinophilia. The appearances initially confused two experienced dermatopathologists.

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