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    Nat Struct Biol. 2000 Nov;7 Suppl:970-2.

    Protein production: feeding the crystallographers and NMR spectroscopists.

    Edwards AM, Arrowsmith CH, Christendat D, Dharamsi A, Friesen JD, Greenblatt JF, Vedadi M.

    Ontario Cancer Institute, Toronto, Canada. aled.edwards@utoronto.ca

    Protein purification efforts for structural genomics will focus on automation for the readily-expressed proteins, and process development for the more difficult ones, such as membrane proteins. Thousands of proteins are expected to be produced in the next few years. The purified proteins will be valuable reagents for the entire research community.

    PMID: 11104003 [PubMed - indexed for MEDLINE]

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