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1: Lancet. 2000 Nov 11;356(9242):1657-8.Click here to read Links
Comment in:
Lancet. 2001 Mar 24;357(9260):955-6.
Lancet. 2001 Mar 24;357(9260):956.
Lancet. 2001 Mar 24;357(9260):956.
Lancet. 2001 Nov 17;358(9294):1734.

Association between acute hypobaric hypoxia and activation of coagulation in human beings.

Bendz B, Rostrup M, Sevre K, Andersen TO, Sandset PM.

The risk of venous thrombosis is thought to be increased by flying. In a study of 20 healthy male volunteers who were suddenly exposed to a hypobaric environment similar to that encountered within aeroplane cabins, markers of activated coagulation transiently Increased by two-fold to eight-fold. We suggest that hypobaric hypoxia, with sedentariness and dehydration, may cause this increased risk of venous thrombosis.

PMID: 11089830 [PubMed - indexed for MEDLINE]