Format

Send to

Choose Destination
See comment in PubMed Commons below
Antimicrob Agents Chemother. 2000 Dec;44(12):3441-3.

High-level fluoroquinolone-resistant clinical isolates of Escherichia coli overproduce multidrug efflux protein AcrA.

Author information

  • 1Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3206, USA.

Erratum in

  • Antimicrob Agents Chemother 2001 Feb;45(2):647.

Abstract

Immunoblotting with antibody against AcrA, an obligatory component of the AcrAB multidrug efflux system, showed that this protein was overexpressed by >/=170% in 9 of 10 clinical isolates of Esherichia coli with high-level ciprofloxacin resistance (MICs, >/=32 microg/ml) but not in any of the 15 isolates for which the MIC was </=1 microg/ml.

PMID:
11083655
PMCID:
PMC90220
[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Write to the Help Desk