Background: One of the most significant complications following genetic amniocentesis is rupture of membranes, reported to occur in 1.15-1.7% of cases. Management of such cases is controversial.
Case: Genetic amniocentesis complicated by ruptured membranes was diagnosed in a 36-year-old woman. The membranes resealed after 48 hours, and the patient had a favorable outcome.
Conclusion: In the case of genetic amniocentesis complicated by ruptured membranes, if chorioamnionitis does not develop, reseal can be expected to occur within seven days in the majority of cases. Thus, conservative management should be the first option.