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The genetic legacy of Paleolithic Homo sapiens sapiens in extant Europeans: a Y chromosome perspective.
Semino O,
Passarino G,
Oefner PJ,
Lin AA,
Arbuzova S,
Beckman LE,
De Benedictis G,
Francalacci P,
Kouvatsi A,
Limborska S,
Marcikiae M,
Mika A,
Mika B,
Primorac D,
Santachiara-Benerecetti AS,
Cavalli-Sforza LL,
Underhill PA.
Dipartimento di Genetica e Microbiologia, Università di Pavia, Via Ferrata 1, 27100 Pavia, Italy. semino@ipvgen.univp.it
A genetic perspective of human history in Europe was derived from 22 binary markers of the nonrecombining Y chromosome (NRY). Ten lineages account for >95% of the 1007 European Y chromosomes studied. Geographic distribution and age estimates of alleles are compatible with two Paleolithic and one Neolithic migratory episode that have contributed to the modern European gene pool. A significant correlation between the NRY haplotype data and principal components based on 95 protein markers was observed, indicating the effectiveness of NRY binary polymorphisms in the characterization of human population composition and history.
PMID: 11073453 [PubMed - indexed for MEDLINE]
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Cited by 56 PubMed Central articles
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Geographical affinities of the HapMap samples.
He M, Gitschier J, Zerjal T, de Knijff P, Tyler-Smith C, Xue Y.
PLoS One. 2009; 4(3):e4684. Epub 2009 Mar 4.
[PLoS One. 2009]
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The genetic legacy of religious diversity and intolerance: paternal lineages of Christians, Jews, and Muslims in the Iberian Peninsula.
Adams SM, Bosch E, Balaresque PL, Ballereau SJ, Lee AC, Arroyo E, López-Parra AM, Aler M, Grifo MS, Brion M, et al.
Am J Hum Genet. 2008 Dec; 83(6):725-36.
[Am J Hum Genet. 2008]
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Identifying genetic traces of historical expansions: Phoenician footprints in the Mediterranean.
Zalloua PA, Platt DE, El Sibai M, Khalife J, Makhoul N, Haber M, Xue Y, Izaabel H, Bosch E, Adams SM, et al.
Am J Hum Genet. 2008 Nov; 83(5):633-42. Epub 2008 Oct 30.
[Am J Hum Genet. 2008]
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