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Rinsho Ketsueki. 2000 Sep;41(9):764-7.

[Adult acute lymphoblastic leukemia presenting a near haploid karyotype].

[Article in Japanese]

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  • 1Department of Hematology, National Kyushu Cancer Center Hospital.


Thirty cases of childhood acute lymphoblastic leukemia (ALL) with a near haploid karyotype (< 30 chromosomes) have been reported so far. However, despite a few cases of severely hypodiploid (30-39 chromosomes) ALL, no near haploid cases have been reported in adult patients. Here, we describe a 64-year-old woman with ALL (L2, CD10+ 19+ 34+ HLA-DR+) presenting a near haploid karyotype of 27, X, +X, +6, +10, +21/54, idem x 2. She died of septic shock during complete remission 6.5 months after the diagnosis.

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