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Am J Med Sci. 2000 Oct;320(4):278-80.

Unilateral internuclear ophthalmoplegia and recovery with thiamine in Wernicke syndrome.

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  • 1Department of Medicine, Huron Hospital/Cleveland Clinic Health System, Ohio 44112, USA. ponondileep@hotmail.com


Internuclear ophthalmoplegia is usually caused by multiple sclerosis, tumors, or vascular lesions of the brain stem. We report a patient with Wernicke syndrome who presented with a right-sided internuclear ophthalmoplegia. He recovered completely with intravenous thiamine (vitamin B1). There were no lesions in the magnetic resonance image (MRI) of the brain, suggesting a derangement at the cellular level as the cause.

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