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Ann Rheum Dis. 2000 Nov;59(11):875-8.

Fatigue in primary Sjögren's syndrome: is there a link with the fibromyalgia syndrome?

Author information

  • 1Centre for Rheumatology, University College London, Arthur Stanley House, 40-50 Tottenham Street, London W1P 9PG, UK. I.Giles@lch.ucl.ac.uk

Abstract

OBJECTIVE:

To determine whether fibromyalgia (FM) is more common in patients with primary Sjögren's syndrome (pSS) who complain of fatigue. The association and prevalence of fatigue and FM was recorded in a group of patients with pSS and a control group of lupus patients, a subset of whom had secondary Sjögren's syndrome (sSS).

METHODS:

74 patients with pSS and 216 patients with lupus were assessed with a questionnaire to identify the presence of fatigue and generalised pain. From the lupus group, in a subset of 117 lupus patients (from the Bloomsbury unit) those with sSS were identified. All patients were studied for the presence of FM.

RESULTS:

50 of 74 patients with pSS (68%) reported fatigue-a prevalence significantly higher than in the lupus group (108/216 (50%); p<0.0087). Fatigue was present in 7/13 (54%) patients with SLE/sSS. FM was present in 9/74 patients with pSS (12%), compared with 11/216 lupus patients (5%), and in none of the patients with SLE/sSS. None of these values corresponds with previously reported figures of the incidence of FM in pSS.

CONCLUSION:

The results show that fatigue in patients with pSS and sSS is not due to the coexistence of FM in most cases. A lower incidence in the United Kingdom of FM in patients with pSS was found than has been previously reported.

PMID:
11053064
[PubMed - indexed for MEDLINE]
PMCID:
PMC1753022
Free PMC Article
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