Curr Biol. 2000 Oct 5;10(19):R695-7.

Actin cytoskeleton: putting a CAP on actin polymerization.

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Program in Molecular Medicine and the Department of Molecular Genetics and Microbiology, University of Massachusetts Medical Center, 373 Plantation Street, Worcester, Massachusetts 01605, USA.

Abstract

Two recent studies have identified a Drosophila homolog of cyclase-associated protein (CAP) as a developmentally important negative regulator of actin polymerization that may also directly mediate signal transduction.

PMID:: 11050402; [PubMed - indexed for MEDLINE]

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A cytoskeletal localizing domain in the cyclase-associated protein, CAP/Srv2p, regulates access to a distant SH3-binding site. [J Biol Chem. 1999]
A cytoskeletal localizing domain in the cyclase-associated protein, CAP/Srv2p, regulates access to a distant SH3-binding site.
Yu J, Wang C, Palmieri SJ, Haarer BK, Field J. J Biol Chem. 1999 Jul 9; 274(28):19985-91.
A cyclase-associated protein regulates actin and cell polarity during Drosophila oogenesis and in yeast. [Curr Biol. 2000]
A cyclase-associated protein regulates actin and cell polarity during Drosophila oogenesis and in yeast.
Baum B, Li W, Perrimon N. Curr Biol. 2000 Aug 24; 10(16):964-73.
Mammalian homolog of the yeast cyclase associated protein, CAP/Srv2p, regulates actin filament assembly. [Cell Motil Cytoskeleton. 2000]
Mammalian homolog of the yeast cyclase associated protein, CAP/Srv2p, regulates actin filament assembly.
Freeman NL, Field J. Cell Motil Cytoskeleton. 2000 Feb; 45(2):106-20.
Review Cyclase-associated proteins: CAPacity for linking signal transduction and actin polymerization. [FASEB J. 2002]
Review Cyclase-associated proteins: CAPacity for linking signal transduction and actin polymerization.
Hubberstey AV, Mottillo EP. FASEB J. 2002 Apr; 16(6):487-99.
Review Regulation of cortical actin networks in cell migration. [Int Rev Cytol. 2003]
Review Regulation of cortical actin networks in cell migration.
Suetsugu S, Takenawa T. Int Rev Cytol. 2003; 229:245-86.

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Cited by 1 PubMed Central article

Domain analysis of the tubulin cofactor system: a model for tubulin folding and dimerization. [BMC Bioinformatics. 2003]
Domain analysis of the tubulin cofactor system: a model for tubulin folding and dimerization.
Grynberg M, Jaroszewski L, Godzik A. BMC Bioinformatics. 2003 Oct 10; 4:46. Epub 2003 Oct 10.

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