Jpn J Pharmacol. 2000 Sep;84(1):86-8.

Effect of intracerebroventricular administration of soybean lecithin transphosphatidylated phosphatidylserine on scopolamine-induced amnesic mice.

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Yakult Central Institute for Microbiological Research, Kunitachi, Tokyo, Japan.

Abstract

The effect of intracerebroventricularly administered soybean lecithin transphosphatidylated phosphatidylserine (SB-tPS) on memory impairment was evaluated by a passive avoidance task. SB-tPS significantly prolonged the step-through latency induced by scopolamine treatment as in our previous report where SB-tPS was orally administered. The same doses of soybean phosphatidylcholine were ineffective. This result indicates that SB-tPS can act on the brain without any peripheral modification.

PMID:: 11043460; [PubMed - indexed for MEDLINE]

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