Leuk Lymphoma. 2000 May;37(5-6):657-62.

B-cell leukemia in a rhesus macaque (Macaca mulatta) infected with simian immunodeficiency virus.

Source

Department of Surgery, Tulane Cancer Center, Tulane University School of Medicine, New Orleans, LA 70112, USA.

Abstract

Conditions associated with abnormal B-cell proliferation have an increased incidence in the HIV-infected population. A longitudinal study conducted at the Tulane Regional Primate Research Center has followed more than 1,000 rhesus macaques infected with simian-immunodeficiency virus (SIV) since 1984. While spontaneous B-cell malignancy in SIV-negative macaques has not been reported, 42 cases of SIV-associated-lymphoma (SAL) have been documented in this cohort. Recently we identified a single case of B-cell leukemia, first suggested by clinical abnormalities and confirmed and further characterized by molecular analysis. The case is important because it models the occurrence of B-cell leukemia in the human AIDS patient and because it extends our understanding of the B-cell lymphoproliferative diseases associated with AIDS.

PMID:: 11042530; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances, Grant Support

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Medical

Mycobacterium avium Complex and Atypical Mycobacterial Infections in the Setting of HIV Infection - HIV InSite

Supplemental Content

Save items

Related citations in PubMed

Rhesus lymphocryptovirus infection during the progression of SAIDS and SAIDS-associated lymphoma in the rhesus macaque. [AIDS Res Hum Retroviruses. 2000]
Rhesus lymphocryptovirus infection during the progression of SAIDS and SAIDS-associated lymphoma in the rhesus macaque.
Habis A, Baskin G, Simpson L, Fortgang I, Murphey-Corb M, Levy LS. AIDS Res Hum Retroviruses. 2000 Jan 20; 16(2):163-71.
Expression of the simian Epstein-Barr virus-encoded latent membrane protein-1 in malignant lymphomas of SIV-infected rhesus macaques. [J Med Virol. 2001]
Expression of the simian Epstein-Barr virus-encoded latent membrane protein-1 in malignant lymphomas of SIV-infected rhesus macaques.
Blaschke S, Hannig H, Buske C, Kaup FJ, Hunsmann G, Bodemer W. J Med Virol. 2001 Sep; 65(1):114-20.
Rhesus rhadinovirus infection in healthy and SIV-infected macaques at Tulane National Primate Research Center. [J Med Primatol. 2003]
Rhesus rhadinovirus infection in healthy and SIV-infected macaques at Tulane National Primate Research Center.
Ruff K, Baskin GB, Simpson L, Murphey-Corb M, Levy LS. J Med Primatol. 2003 Feb; 32(1):1-6.
Origins of simian immunodeficiency virus infection in macaques at the New England Regional Primate Research Center. [J Med Primatol. 1995]
Origins of simian immunodeficiency virus infection in macaques at the New England Regional Primate Research Center.
Mansfield KG, Lerch NW, Gardner MB, Lackner AA. J Med Primatol. 1995 May; 24(3):116-22.
Review Comparative pathobiology of HIV- and SIV-associated lymphoma. [AIDS Res Hum Retroviruses. 2001]
Review Comparative pathobiology of HIV- and SIV-associated lymphoma.
Baskin GB, Cremer KJ, Levy LS. AIDS Res Hum Retroviruses. 2001 May 20; 17(8):745-51.

See reviews... See all...

Cited by 1 PubMed Central article

Novel Kaposi's sarcoma-associated herpesvirus homolog in baboons. [J Virol. 2003]
Novel Kaposi's sarcoma-associated herpesvirus homolog in baboons.
Whitby D, Stossel A, Gamache C, Papin J, Bosch M, Smith A, Kedes DH, White G, Kennedy R, Dittmer DP. J Virol. 2003 Jul; 77(14):8159-65.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

B-cell leukemia in a rhesus macaque (Macaca mulatta) infected with simian immuno...
B-cell leukemia in a rhesus macaque (Macaca mulatta) infected with simian immunodeficiency virus.
Leuk Lymphoma. 2000 May ;37(5-6):657-62.

PubMed
Life and death of the pancreatic beta cells.
Life and death of the pancreatic beta cells.
Trends Endocrinol Metab. 2000 Nov ;11(9):375-8.

PubMed
The classic: Wiring of the vertebrae as a means of immobilization in fracture an...
The classic: Wiring of the vertebrae as a means of immobilization in fracture and Potts' disease. Berthold E. Hadra. Med Times and Register, Vol22, May 23, 1891.
Clin Orthop Relat Res. 1975 Oct ;(112):4-8.

PubMed
Structure, biological activity of the upstream regulatory sequence, and conserve...
Structure, biological activity of the upstream regulatory sequence, and conserved domains of a middle molecular mass neurofilament gene of Xenopus laevis.
Brain Res Mol Brain Res. 2000 Oct 20 ;82(1-2):35-51.

PubMed
Induction and detection of antibodies to squalene.
Induction and detection of antibodies to squalene.
J Immunol Methods. 2000 Nov 1 ;245(1-2):1-14.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

B-cell leukemia in a rhesus macaque (Macaca mulatta) infected with simian immunodeficiency virus.

Source

Abstract

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Grant Support

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Supplemental Content

Save items

Related citations in PubMed

Cited by 1 PubMed Central article

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information