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J Nat Prod. 2000 Sep;63(9):1286-7.

Bioactive sesquiterpenes from the basidiomycete Resupinatus leightonii.

Author information

  • 1Institute for Biotechnology and Drug Research (IBWF e.V.), D-67663 Kaiserslautern, Germany.

Abstract

1(10),4-Germacradiene-2,6,12-triol (1), a new germacrane sesquiterpene, and 1,6-farnesadiene-3,10,11-triol (2), a known nerolidol derivative, were isolated from submerged cultures of the basidiomycete Resupinatus leightonii. Both compounds inhibited cAMP-induced appressorium formation in Magnaporthe grisea and showed cytotoxic activity. The structure of 1 was determined by NMR and mass spectroscopic methods.

PMID:
11000039
[PubMed - indexed for MEDLINE]
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