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Int J Obes Relat Metab Disord. 2000 Jun;24 Suppl 2:S1-3.

Adipose tissue as an endocrine organ.

Author information

  • Laboratoire de Biologie du Développement du Tissu Adipeux, Centre de Biochimie, UNSA, Faculté des Sciences, Nice, France. ailhaud@unice.fr

Abstract

The objective is to present a brief overview of peptide and non-peptide factors secreted from adipocytes and to describe some studies on the postulated role of the locally active triad angiotensinogen/angiotensinII/ prostacyclin in the development/enlargement of adipose tissue mass and increased blood pressure. In addition to the role of adipose tissue as an endocrine organ, the results emphasize the autocrine/paracrine mechanisms which are postulated to play a role in adipose tissue development and enlargement.

PMID:
10997598
[PubMed - indexed for MEDLINE]
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