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Farmaco. 2000 May;55(5):410-3.

Photostability determination of arbutin, a vegetable whitening agent.

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  • 1Laboratory of Industrial Pharmacy, School of Pharmacy, University of Nantes, France.


The target of this research was to evaluate the photostability at various pH values of 1.20 x 10(-4) M aqueous solution of arbutin (lambda max = 267 nm; epsilon = 7500 M-1.cm-1). This photodegradation appeared to follow first-order kinetics whatever the pH. The degradation rate constant was calculated to be 5.5 x 10(-4), 7.0 x 10(-4) and 24.1 x 10(-4) min-1, respectively at pH 5, 7 and 9.

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