Occupational allergic airbone contact dermatitis and delayed bronchial asthma from epoxy resin revealed by bronchial provocation test

Eur J Dermatol. 2000 Aug;10(6):475-7.

Abstract

Diglycidyl ether of bisphenol A (DGEBA) epoxy resins belong to the most common causes of occupational allergic contact dermatitis. DGEBA has on rare occasions caused occupational asthma. Here we present a patient who first developed occupational allergic contact dermatitis (ACD) caused by a single accidental exposure to DGEBA. Then, on continued occupational exposure to DGEBA, the patient developed occupational asthma from DGEBA, in addition to ACD. A bronchial provocation test with DGEBA caused a 36% drop in the peak expiratory flow, reflecting a delayed type of occupational asthma. This bronchial provocation test caused a strong dermatitis of the exposed skin of the face, in accordance with airborne ACD from DGEBA.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Air Pollutants, Occupational / adverse effects*
  • Asthma / chemically induced*
  • Asthma / pathology
  • Benzhydryl Compounds
  • Bronchial Provocation Tests
  • Dermatitis, Allergic Contact / etiology*
  • Dermatitis, Allergic Contact / pathology
  • Dermatitis, Occupational / etiology*
  • Dermatitis, Occupational / pathology
  • Epoxy Compounds / adverse effects
  • Epoxy Resins / adverse effects*
  • Humans
  • Hypersensitivity, Delayed / chemically induced*
  • Hypersensitivity, Delayed / pathology
  • Male

Substances

  • Air Pollutants, Occupational
  • Benzhydryl Compounds
  • Epoxy Compounds
  • Epoxy Resins
  • 2,2-bis(4-glycidyloxyphenyl)propane