Imprinting: focusing on the center

Curr Opin Genet Dev. 2000 Oct;10(5):550-4. doi: 10.1016/s0959-437x(00)00126-x.

Abstract

Recent studies have focused on the identification of imprinting centers and on the elucidation of the mechanisms by which they control imprinting. These studies begin to shed light on the means by which imprinting marks are established in the gametes and on the various molecular strategies utilized to execute differential expression of the two parental alleles.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Alleles
  • Animals
  • Autoantigens / genetics
  • DNA Methylation
  • Genomic Imprinting*
  • Humans
  • Receptor, IGF Type 2 / genetics
  • Ribonucleoproteins, Small Nuclear*
  • snRNP Core Proteins

Substances

  • Autoantigens
  • Receptor, IGF Type 2
  • Ribonucleoproteins, Small Nuclear
  • snRNP Core Proteins