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Appl Environ Microbiol. 2000 Sep;66(9):4157-60.

Transformation of triclosan by Trametes versicolor and Pycnoporus cinnabarinus.

Author information

  • 1Institute of Microbiology and Molecular Biology, Ernst-Moritz-Arndt-University, D-17487 Greifswald, Germany. kai.hundt@plasmaselect.com

Abstract

We investigated the ability of Trametes versicolor and Pycnoporous cinnabarinus to metabolize triclosan. T. versicolor produced three metabolites, 2-O-(2,4,4'-trichlorodiphenyl ether)-beta-D-xylopyranoside, 2-O-(2,4,4'-trichlorodiphenyl ether)-beta-D-glucopyranoside, and 2,4-dichlorophenol. P. cinnabarinus converted triclosan to 2,4, 4'-trichloro-2'-methoxydiphenyl ether and the glucoside conjugate known from T. versicolor. The conjugates showed a distinctly lower cytotoxic and microbicidal activity than triclosan did.

PMID:
10966448
[PubMed - indexed for MEDLINE]
PMCID:
PMC92278
Free PMC Article
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