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Br J Psychiatry. 2000 Jul;177:26-32.

Cognitive and behavioural functioning in men with schizophrenia both before and shortly after first admission to hospital. Cross-sectional analysis.

Author information

  • 1Bar Ilan University, Ramat Gan, Israel. rabinowz@mail.biu.ac.il

Abstract

BACKGROUND:

The extent of premorbid changes associated with the onset of schizophrenia are debated.

AIMS:

The study examined cognitive and behavioural functioning prior to, and after, first hospitalisation for schizophrenia.

METHOD:

Data from the Israeli Draft Board Register of intelligence, social functioning and behaviour testing for all Israeli males aged 16-17 was linked with data from the National Psychiatric Hospitalisation Case Register. This identified 692 men who had been admitted to hospital for schizophrenia. Cases and non-cases matched on age and school were compared, as were cases aggregated by the time that had elapsed between testing and first admission to hospital.

RESULTS:

Cases performed worse than non-cases on all measures. On Social Functioning and on Raven's Progressive Matrices-R, differences between cases and non-cases were progressively greater for cases admitted closer to the time of testing. These differences were greatest for persons tested after first psychiatric hospitalisation.

CONCLUSIONS:

The results confirm premorbid deficits associated with schizophrenia and support the hypothesis that decline is progressive.

PMID:
10945084
[PubMed - indexed for MEDLINE]
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