Format

Send to

Choose Destination
See comment in PubMed Commons below
Annu Rev Nutr. 2000;20:339-63.

Mitochondrial uncoupling proteins in energy expenditure.

Author information

  • 1Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA. kozaklp@pbrc.edu

Abstract

Four recently discovered homologues of the brown adipose tissue-specific mitochondrial uncoupling protein (UCP1) vary from 29% to 58% in their similarity to UCP1. Although these homologues share important structural features with UCP1 and like UCP1 can reduce the mitochondrial membrane potential when expressed in yeast, there is no clear evidence that they can function thermogenically in vivo. On the other hand, evidence continues to accumulate indicating that the up-regulation of Ucp1 reduces excessive adiposity.

[PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Other Literature Sources

PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Atypon
    Loading ...
    Write to the Help Desk