J Clin Endocrinol Metab. 1975 Jun;40(6):1110-3.

Myotonia dystrophica: Studies on gonadal function using luteinizing hormone-releasing hormone (LRH).

Sagel J, Distiller LA, Morley JE, Isaacs H, Kay G, Van Der Walt A.

Abstract

Eight men and four women with myotonia dystrophica were investigated. The gonadotropin responses to 100 mug luteinizing hormone-releasing hormone (LRH) were studied, and serum testosterone assayed. In the men with testicular atrophy a high basal follicle stimulating hormone was found with an exaggerated response to LRH. Although the mean basal luteinizing hormone was not significantly elevated, there was an excessive response to LRH, which was possibly conditioned by the lower mean testoerone levels in this group. This study provides biochemical indices of both the primary nature of the testicular damage and the disproportionately greater involvement of the seminiferous tubules. The pituitary-gonadal axis was normal in the women.

PMID:: 1094029; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Comparative Study

MeSH Terms

Substances

LinkOut - more resources

Supplemental Content

Save items

Related citations in PubMed

Effect of renal transplantation on pituitary gonadal function. [Metabolism. 1978]
Effect of renal transplantation on pituitary gonadal function.
Morley JE, Distiller LA, Unterhalter S, Myers JB, Rabkin R, Katz M. Metabolism. 1978 Jul; 27(7):781-5.
Pituitary-gonadal function in male patients with myotonic dystrophy- serum luteinizing hormone, follicle stimulating hormone and testosterone levels and histological dmaage of the testis. [Acta Endocrinol (Copenh). 1977]
Pituitary-gonadal function in male patients with myotonic dystrophy- serum luteinizing hormone, follicle stimulating hormone and testosterone levels and histological dmaage of the testis.
Takeda R, Ueda M. Acta Endocrinol (Copenh). 1977 Feb; 84(2):382-9.
Prolonged pulsatile administration of luteinizing hormone-releasing hormone in prepubertal children: diagnostic and physiologic aspects. [J Clin Endocrinol Metab. 1985]
Prolonged pulsatile administration of luteinizing hormone-releasing hormone in prepubertal children: diagnostic and physiologic aspects.
Delemarre-van de Waal HA, Van den Brande JL, Schoemaker J. J Clin Endocrinol Metab. 1985 Nov; 61(5):859-67.
Review Dynamic testing in the evaluation of male gonadal function. [J Endocrinol Invest. 2003]
Review Dynamic testing in the evaluation of male gonadal function.
De Martino MU, Pastore R, Caprio M, Frajese G, Fabbri A. J Endocrinol Invest. 2003; 26(7 Suppl):107-13.
Review [The prehypophyseal-gonadal system in the normal male and in some forms of testicular dyscrinism. Evaluation studies in basic conditions and after stimulation]. [Minerva Med. 1979]
Review [The prehypophyseal-gonadal system in the normal male and in some forms of testicular dyscrinism. Evaluation studies in basic conditions and after stimulation].
Mazzi C. Minerva Med. 1979 Mar 30; 70(15):1043-56.

See reviews... See all...

Cited by 2 PubMed Central articles

The reproductive outcome of female patients with myotonic dystrophy type 1 (DM1) undergoing PGD is not affected by the size of the expanded CTG repeat tract. [J Assist Reprod Genet. 2010]
The reproductive outcome of female patients with myotonic dystrophy type 1 (DM1) undergoing PGD is not affected by the size of the expanded CTG repeat tract.
Verpoest W, Seneca S, De Rademaeker M, Sermon K, De Rycke M, De Vos M, Haentjens P, Devroey P, Liebaers I. J Assist Reprod Genet. 2010 Jun; 27(6):327-33. Epub 2010 Mar 11.
Premature ovarian failure. [Bull N Y Acad Med. 1986]
Premature ovarian failure.
Jewelewicz R, Schwartz M. Bull N Y Acad Med. 1986 Apr; 62(3):219-36.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound
PubChem chemical compound records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records. Multiple substance records may contribute to the PubChem compound record.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Gene (OMIM)
Gene records associated with Online Mendelian Inheritance in Man (OMIM) records that cite the current articles in their reference lists.
Nucleotide (Weighted)
Nucleotide records associated with the current articles through the Gene database. These are the related sequences on the Gene record that are added manually by NCBI.
OMIM (calculated)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as references in the light bulb links within or in the citations at the end of the OMIM record. The references available through the light bulb link are collected using the PubMed related articles algorithm to identify records with similar terminology to the OMIM record.
OMIM (cited)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as reference cited at the end of the OMIM record.
Protein (Weighted)
Protein records associated with the current articles through related Gene database records. These are the related sequences on the Gene record that are added manually by NCBI.
Substance
PubChem chemical substance records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Myotonia dystrophica: Studies on gonadal function using luteinizing hormone-rele...
Myotonia dystrophica: Studies on gonadal function using luteinizing hormone-releasing hormone (LRH).
J Clin Endocrinol Metab. 1975 Jun ;40(6):1110-3.

PubMed
Topical tacrolimus may be effective in the treatment of oral and perineal Crohn'...
Topical tacrolimus may be effective in the treatment of oral and perineal Crohn's disease.
Gut. 2000 Sep ;47(3):436-40.

PubMed
A homologue of an operon required for DNA transfer in Agrobacterium is required ...
A homologue of an operon required for DNA transfer in Agrobacterium is required in Brucella abortus for virulence and intracellular multiplication.
J Bacteriol. 2000 Sep ;182(17):4849-55.

PubMed
Lipids on the move: phosphoinositide 3-kinases in leukocyte function.
Lipids on the move: phosphoinositide 3-kinases in leukocyte function.
Immunol Today. 2000 Jun ;21(6):260-4.

PubMed
Secretion of endothelin converting enzyme-1a: the hydrophobic signal anchor doma...
Secretion of endothelin converting enzyme-1a: the hydrophobic signal anchor domain alone is not sufficient to promote membrane localization.
Mol Cell Biochem. 2000 May ;208(1-2):45-51.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Myotonia dystrophica: Studies on gonadal function using luteinizing hormone-releasing hormone (LRH).

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

Cited by 2 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information