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    Fitoterapia. 2000 Aug;71 Suppl 1:S29-37.

    Grapefruit: the last decade acquisitions.

    Tirillini B.

    Source

    Istituto di Botanica, Università di Urbino Via Bramante, 28-61029, Urbino, Italy.

    Abstract

    This review reports the last decade acquisitions on grapefruit. New coumarins and limonoids were isolated and characterised. The bioavailability of many drugs was tested with grapefruit juice (GJ) coadministration; the inhibition on cytochrome P450 seems due to a synergic action between flavonoids and coumarins. Antimicrobial, antifeeding, insecticidal, and antitumour activities were also reported.

    PMID:
    10930710
    [PubMed - indexed for MEDLINE]

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