Bone marrow and peripheral blood hematopoietic stem cell transplantation: focus on autografting

Clin Chem. 2000 Aug;46(8 Pt 2):1239-51.

Abstract

This review focuses on certain of the principles involved in high-dose chemotherapy and radiation therapy along with autologous hematopoietic stem cell transplantation for the treatment of certain malignancies. In addition, the evidence, wherever possible based on randomized data, for the application of this approach in certain malignancies is reviewed. The malignancies highlighted include acute myeloid leukemia, acute lymphoblastic leukemia, non-Hodgkin lymphoma, Hodgkin disease, and breast cancer.

Publication types

  • Review

MeSH terms

  • Bone Marrow Transplantation*
  • Breast Neoplasms / drug therapy
  • Breast Neoplasms / radiotherapy
  • Breast Neoplasms / therapy
  • Combined Modality Therapy
  • Female
  • Hematopoietic Stem Cell Transplantation*
  • Hodgkin Disease / drug therapy
  • Hodgkin Disease / radiotherapy
  • Hodgkin Disease / therapy
  • Humans
  • Leukemia, Myeloid / drug therapy
  • Leukemia, Myeloid / radiotherapy
  • Leukemia, Myeloid / therapy
  • Lymphoma, Non-Hodgkin / drug therapy
  • Lymphoma, Non-Hodgkin / radiotherapy
  • Lymphoma, Non-Hodgkin / therapy
  • Multiple Myeloma / drug therapy
  • Multiple Myeloma / radiotherapy
  • Multiple Myeloma / therapy
  • Neoplasms / drug therapy
  • Neoplasms / radiotherapy
  • Neoplasms / therapy*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / radiotherapy
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy
  • Randomized Controlled Trials as Topic
  • Transplantation, Autologous