Format

Send to

Choose Destination
See comment in PubMed Commons below
Neurology. 2000 Jul 12;55(1):139-41.

Aura in some patients with familial hemiplegic migraine can be stopped by intranasal ketamine.

Author information

  • 1Institute of Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.

Abstract

Migraine aura is probably caused by cortical-spreading depression. No treatment for acute and severe migraine aura has been described previously. The effect of ketamine (25 mg intranasally) was studied in 11 patients with severe, disabling auras resulting from familial hemiplegic migraine. In five patients ketamine reproducibly reduced the severity and duration of the neurologic deficits, whereas in the remaining six patients no beneficial effect was seen. Ketamine offers, for the first time, a possible treatment option for severe and prolonged aura.

PMID:
10891926
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk