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    Nat Cell Biol. 2000 Jul;2(7):463-5.

    Presenilins are required for gamma-secretase cleavage of beta-APP and transmembrane cleavage of Notch-1.

    Source

    Department of Neurology, Harvard Medical School and Division of Neuroscience, Children's Hospital, Boston, MA 02115, USA.

    PMID:
    10878814
    [PubMed - indexed for MEDLINE]

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