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Semin Interv Cardiol. 2000 Mar;5(1):7-13.

Mortality and morbidity rates after conventional abdominal aortic aneurysm repair.

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  • 1Department of Surgery, University Medical Center Utrecht, The Netherlands. j.d.blankensteijn chir.azu.nl.

Abstract

AIM:

To grade and analyse by levels of evidence the mortality and morbidity rates of elective abdominal aortic aneurysm (AAA) surgery as reported over the past 12 years.

METHODS:

Articles on elective AAA surgery published between 1985 and 1996 were retrieved and classified into 5 levels of evidence. Level 1 contains prospective studies and is subdivided into population-based (Level 1a) and hospital-based (Level 1b) studies. Level 2 includes retrospective studies, subdivided into population-based (Level 2a), hospital-based (Level 2b), and hospital-based studies concerning a specified group of selected patients (Level 2c). Operative mortality and systemic and local/vascular complication rates and 95% confidence intervals were calculated per level of evidence.

RESULTS:

Seventy-two articles describing a total of 37,654 patients could be included: 2 level 1a studies (patient total: 692), 9 Level 1b studies (patient total: 1,677), 13 Level 2a studies (patient total 21,409), 32 Level 2b studies (patient total: 12,019), and 16 Level 2c studies (patient total: 1,857). The mean 30-day mortality rates of the two population-based levels were similar: 8.2% (6.4%-10.6%) for the prospective (1a) and 7.4% (7.0%-7.7%) for the retrospective series (2a). These figures were significantly higher than the remarkably similar hospital-based mortality rates: 3.8% (3.0%-4.8%) for the prospective (1b), 3.8% (3.5%-4.2%) for the retrospective (2b), and 3.5% (2.8%-4.4%) for selected patient group studies (2c). The most frequent complication was of cardiac origin. In the population-based series the cardiac complication rate was 10.6% (8.5%-13.2%) and 11.1% (9.1%-13.6%) for Levels 1a and 2a respectively. This compared well with the 12.0% (10.5%-13.9%) for the prospective, hospital-based series (Level 1b). The cardiac complication rates in the retrospective, hospital-based studies was significantly lower: 8.9% (8.4%-9.5%) and 6.1% (4.9%-7.6%) for Levels 2b and 2c respectively.

CONCLUSION:

There is a clear and consistent disagreement in reported mortality rates between hospital-based and population-based studies of elective AAA-surgery. Prospective studies give the best documentation of postoperative morbidity.

PMID:
10875218
[PubMed - indexed for MEDLINE]
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