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Curr Biol. 2000 Jun 15;10(12):R452-5.

Evolution: hox genes and the cellared wine principle.

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  • 1Department of Genetics, North Carolina State University, Raleigh 27695-7614, USA.


Two Drosophila Hox genes involved in segmentation, fushi tarazu and bicoid, appear to have acquired these roles by functional divergence from classical homeotic genes. Recent results indicate how genes with critical functions in development can evolve completely different functions among species.

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