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Int J Cancer. 2000 Jul 15;87(2):232-5.

Seropositivity to human herpesvirus 8 in relation to sexual history and risk of sexually transmitted infections among women.

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  • 1Department of Microbiology-Immunology and Virology, Centro di Riferimento Oncologico, Istituto Nazionale Tumori, Aviano, Italy.


The mode of transmission of human herpesvirus 8 (HHV8) was investigated in two seroepidemiological studies of Swedish women who completed a questionnaire about sexual behavior. Seropositivity for HHV8 antibodies, measured using an indirect immunofluorescence assay, was linked to a high number (>10) of sexual partners (P < 0.004). It also correlated strongly with a history of other sexually transmitted diseases (STD; P < 0.0001), in particular with a history of Chlamydia trachomatis infection and condyloma acuminata. There was appreciable HHV8 seropositivity already among virginal or monogamous women (9%). In summary, HHV8 transmission to women in Sweden may occur nonsexually. When sexual transmission occurs, it appears to be associated with high risk-taking sexual behavior.

Copyright 2000 Wiley-Liss, Inc.

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