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Nutr Rev. 2000 May;58(5):138-44.

Hypervitaminosis A and bone.

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  • 1Institute on Aging, University of Wisconsin, Madison 53706, USA.

Abstract

Animal, human, and in vitro data all indicate that excess vitamin A stimulates bone resorption and inhibits bone formation. This combination would be expected to produce bone loss and to contribute to osteoporosis development and may occur with relatively low vitamin A intake. It is possible that unappreciated hypervitaminosis A contributes to osteoporosis pathogenesis.

PMID:
10860393
[PubMed - indexed for MEDLINE]
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