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Biochim Biophys Acta. 2000 Jun 21;1492(1):237-41.

The human SOX18 gene: cDNA cloning and high resolution mapping.

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  • 1Institute of Molecular Genetics and Genetic Engineering, Vojvode Stepe 444a, PO Box 794, 11001 Belgrade, Yugoslavia.


SOX genes comprise a family of genes that are related to the mammalian sex determining gene SRY and these genes play key roles during animal development. We report here cloning and characterisation of the human SOX18 gene. SOX18 gene is expressed in foetal brain as well as in a wide range of foetal and adult tissues indicating its function is not restricted to early development. Mapping analysis has revealed that SOX18 gene is located on human chromosome 20q13.3, 27.29 cR distal from the marker D20S173.

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