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Fertil Steril. 2000 Jun;73(6):1155-8.

Blastocyst score affects implantation and pregnancy outcome: towards a single blastocyst transfer.

Author information

  • 1Colorado Center for Reproductive Medicine, Englewood, Colorado, USA. dgardner@colocrm.com

Abstract

OBJECTIVE:

To determine the relationship between blastocyst score and pregnancy outcome.

DESIGN:

Retrospective review of blastocyst transfer in an IVF clinic.

SETTING:

Private assisted reproductive technology unit.

PATIENT(S):

107 patients undergoing blastocyst culture and transfer of two embryos.

INTERVENTION(S):

Culture of all pronucleate embryos in sequential media to the blastocyst stage (day 5), followed by transfer of two blastocysts.

MAIN OUTCOME MEASURE(S):

Implantation rates, pregnancy rates, and twinning were analyzed.

RESULT(S):

When a patient received two top-scoring blastocysts (64% of patients), implantation and pregnancy rates were 70% and 87%, respectively. The twinning rate in this group was 61%. When only one top-quality blastocyst was available for transfer (21% of patients), the implantation and pregnancy rates were 50% and 70%. The twinning rate for this group was 50%. In contrast, when only low-scoring blastocysts were available for transfer (15% of patients), implantation and pregnancy rates were 28% and 44%, and the twinning rate was 29%. No monozygotic twins were observed in this group of patients.

CONCLUSION(S):

The ability to transfer one high-scoring blastocyst should lead to pregnancy rates greater than 60%, without the complication of twins.

PMID:
10856474
[PubMed - indexed for MEDLINE]
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