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    Can J Surg. 2000 Jun;43(3):212-6.

    Perioperative blood transfusion and albumin administration are independent risk factors for the development of postoperative infections after colorectal surgery.

    Source

    Department of Surgery, St. Boniface General Hospital, Winnipeg, Man. Mark_Torchia@sbrc.umanitoba.ca

    Abstract

    OBJECTIVES:

    To determine whether transfused colorectal surgery patients were at increased risk for postoperative infections in a tertiary care teaching hospital and whether transfusion alone was the only significant risk factor.

    DESIGN:

    A retrospective study.

    SETTING:

    A single tertiary care teaching hospital.

    PATIENTS:

    All patients admitted to St. Boniface General Hospital, Winnipeg, for colorectal surgery during the period Apr. 1, 1995, through Mar. 31, 1996, were studied (N = 154).

    RESULTS:

    The overall infection rate was 17%: nontransfused patients, 13%, and transfused patients, 28% (p < 0.038). Patients who received albumin perioperatively had a significantly higher infection rate (38%) than those who did not (13%) (p < 0.001). Stepwise logistic regression analysis identified transfusion and albumin administration as the only independent risk factors for postoperative infection.

    CONCLUSION:

    Perioperative transfusion or albumin administration significantly increases the risk of postoperative infection in colorectal surgery patients.

    PMID:
    10851416
    [PubMed - indexed for MEDLINE]
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