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    Curr Opin Neurobiol. 2000 Jun;10(3):370-4.

    Homer: a link between neural activity and glutamate receptor function.

    Source

    Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

    Abstract

    The proteins of the Homer family bind to proline-rich sequences in group I metabotropic glutamate receptors, inositol trisphosphate receptors, ryanodine receptors, and Shank family proteins. Homer proteins also self associate and function as adaptors to couple interacting proteins. Recent observations indicate a role for Homer complexes in signal transduction, synaptogenesis and receptor trafficking.

    PMID:
    10851183
    [PubMed - indexed for MEDLINE]

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