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Curr Opin Neurobiol. 2000 Jun;10(3):342-51.

Synaptic kainate receptors.

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  • 1Departments of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94143, USA.


Kainate receptors are a family of ionotropic glutamate receptors with poorly understood functions. Recent evidence firmly establishes kainate receptors as postsynaptic mediators of synaptic transmission. A second, presynaptic, modulatory role of kainate receptors has also been suggested, although the mechanism(s) involved remain controversial.

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