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Bioorg Med Chem Lett. 2000 May 15;10(10):1043-5.

Antimycobacterial activity of ionic fullerene derivatives.

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  • 1Dipartimento di Scienze Farmaceutiche, Universit√† di Trieste, Italy.

Abstract

Positively charged fullerene derivatives, moderately soluble in water:DMSO 9:1, have been tested using three strains of Mycobacterium spp. Some compounds inhibit the growth of Mycobacterium tuberculosis, a human clinical isolate, particularly virulent and resistant, at doses as low as 5 microg/mL.

PMID:
10843212
[PubMed - indexed for MEDLINE]
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