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    Indoor Air. 2000 Mar;10(1):13-8.

    Determination of microbial colonisation in water-damaged buildings using chemical marker analysis by gas chromatography-mass spectrometry.

    Source

    Lund University, Department of Infectious Diseases and Medical Microbiology, Sweden.

    Abstract

    Gas chromatography-mass spectrometry was used to determine the microbial contents of building materials subjected to water damage in a laboratory experiment and of materials collected from houses affected by water during the flood in Klodzko in south-western Poland, July 1997. The samples were examined for 3-hydroxy fatty acids, markers of bacterial endotoxin, and ergosterol, marker of fungal biomass. The amounts of both 3-hydroxy fatty acids and ergosterol were higher in materials that had been exposed to water than in unexposed ones. All markers were stable in the building materials for at least 6 weeks at room temperature and could thus be used to reveal microbial contamination even when cultivation results for bacteria and fungi were negative. Direct measurement of 3-hydroxy fatty acids and ergosterol in human environments could be a useful method, e.g. in monitoring indoor air as regards presence of potentially harmful microorganisms and microbial constituents.

    PMID:
    10842456
    [PubMed - indexed for MEDLINE]

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