-
Immunoradiometric assay of factor VIII related antigen, with observations in 32 patients with von Willebrand's disease.
A solid phase non-competitive immunoradiometric assay (IRMA) has been developed which allows measurement of factor VIII related antigen (VIIIR:AG) levels in normal plasma as low as 2.5 x 10(-4) U/ml. The assay is based on the extraction of VIIIR:AG from test plasma by means of polystrene tubes coated with a specific unlabelled anti-VIIIR:AG rabbit antiserum and subsequent labelling of the extracted antigen with 125I-labelled anti-VIIIR:AG rabbit IgG.
PMID: 1083743 [PubMed - indexed for MEDLINE]
-
Cited by 10 PubMed Central articles
-
ReviewHaemophilia: strategies for carrier detection and prenatal diagnosis.
Peake IR, Lillicrap DP, Boulyjenkov V, Briet E, Chan V, Ginter EK, Kraus EM, Ljung R, Mannucci PM, Nicolaides K.
Bull World Health Organ. 1993; 71(3-4):429-58.
[Bull World Health Organ. 1993]
-
Studies on hemophilia A in Sardinia bearing on the problems of multiple allelism, carrier detection, and differential mutation rate in the two sexes.
Filippi G, Mannucci PM, Coppola R, Farris A, Rinaldi A, Siniscalco M.
Am J Hum Genet. 1984 Jan; 36(1):44-71.
[Am J Hum Genet. 1984]
-
Homozygous and heterozygous deletions of the von Willebrand factor gene in patients and carriers of severe von Willebrand disease.
Ngo KY, Glotz VT, Koziol JA, Lynch DC, Gitschier J, Ranieri P, Ciavarella N, Ruggeri ZM, Zimmerman TS.
Proc Natl Acad Sci U S A. 1988 Apr; 85(8):2753-7.
[Proc Natl Acad Sci U S A. 1988]
- » See all...