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Am J Obstet Gynecol. 2000 May;182(5):1021-3.

Urinary incontinence and pelvic organ prolapse in women with Marfan or Ehlers Danlos syndrome.

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  • 1Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, USA.

Abstract

OBJECTIVE:

This study was undertaken to determine the prevalence of urinary incontinence and pelvic organ prolapse in a cohort of women with either Marfan syndrome or Ehlers-Danlos syndrome.

STUDY DESIGN:

Female patients with either Marfan syndrome or Ehlers-Danlos syndrome were identified through a medical records search at two urban hospitals. Each patient's medical record was reviewed, and the history of pelvic organ prolapse and urinary incontinence was obtained through telephone interview.

RESULTS:

Twelve women with Marfan syndrome were identified. Among these women 5 (42%) reported a history of urinary incontinence and 4 (33%) reported a history of pelvic organ prolapse. Eight women with Ehlers-Danlos syndrome were identified. Among these women 4 (50%) reported a history of urinary incontinence and 6 (75%) reported a history of pelvic organ prolapse.

CONCLUSIONS:

Women with Marfan or Ehlers-Danlos syndrome have high rates of urinary incontinence and pelvic organ prolapse. This finding supports the hypothesized etiologic role of connective tissue disorders as a factor in the pathogenesis of these conditions.

PMID:
10819815
[PubMed - indexed for MEDLINE]
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