Acetalization of alkenes catalyzed by Pd(OAc)2/NPMoV supported on activated carbon under a dioxygen atmosphere

A Kishi; S Sakaguchi; Y Ishii

doi:10.1021/ol990410w

Acetalization of alkenes catalyzed by Pd(OAc)2/NPMoV supported on activated carbon under a dioxygen atmosphere

Org Lett. 2000 Feb 24;2(4):523-5. doi: 10.1021/ol990410w.

Authors

A Kishi¹, S Sakaguchi, Y Ishii

Affiliation

¹ Department of Applied Chemistry, Faculty of Engineering & High Technology Research Center, Kansai University, Suita, Osaka, Japan.

PMID: 10814367
DOI: 10.1021/ol990410w

Abstract

[reaction: see text] The acetalization of terminal alkenes such as ethyl acrylate and acrylonitrile with alcohols under O2 was efficiently achieved by Pd(OAc)2 supported on activated carbon combined with molybdovanadophosphate (NPMoV). For example, ethyl acrylate was subjected to acetalization with EtOH acidified by CH3SO3H under O2 (1 atm) in the presence of [8 wt%Pd(OAc)2/C] and NPMoV to form ethyl 3,3-diethoxypropionate in quantitative yield.