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Cancer Genet Cytogenet. 2000 May;119(1):37-41.

A case of papillary meningioma with a t(1;4)(q44;q21).

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  • 1Department of Pathology, Fukuoka University School of Medicine, Fukuoka, Japan.

Abstract

We report the results of cytogenetic analyses of three cases of meningiomas. The first case, a papillary meningioma, showed only one cytogenetic abnormality, 46,XX,t(1;4)(q44;q21). In contrast, the other two benign fibroblastic meningiomas showed loss of chromosome 22. Loss and/or rearrangement of chromosomes other than chromosome 22 appears to be associated with a more aggressive clinical course. It is suggested that a sole cytogenetic abnormality with a normal chromosome 22 indicates an atypical nature of meningioma.

PMID:
10812169
[PubMed - indexed for MEDLINE]
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