Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1975 Aug 6;196(2):199-204.

In vitro estrone-estradiol-17beta interconversion in the cornea, lens, iris and retina of the rabbit eye.

Abstract

Estrone and estradiol-17beta were incubated with various eye tissues of female rabbits. The interconversion of both estrogenes by the action of 17beta-hydroxysteroid dehydrogenase decreased in the sequence cornea, iris, retina, and lens. In a smaller yield estradiol-17alpha was also formed from estrone. The cornea seems to be an active estrogen-metabolizing tissue. The role of estrogens and progestogens in the tissues of the anterior eye segment is briefly discussed.

PMID:: 1080648; [PubMed - indexed for MEDLINE]

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In vitro estrone-estradiol-17beta interconversion in the cornea, lens, iris and retina of the rabbit eye.

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