J Pediatr. 2000 May;136(5):679-81.

Iatrogenic exposure to mercury after hepatitis B vaccination in preterm infants.

Stajich GV, Lopez GP, Harry SW, Sexson WR.

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Mercer University, Southern School of Pharmacy, Atlanta, Georgia 30341, USA.

Abstract

Thimerosal, a derivative of mercury, is used as a preservative in hepatitis B vaccines. We measured total mercury levels before and after the administration of this vaccine in 15 preterm and 5 term infants. Comparison of pre- and post-vaccination mercury levels showed a significant increase in both preterm and term infants after vaccination. Additionally, post-vaccination mercury levels were significantly higher in preterm infants as compared with term infants. Because mercury is known to be a potential neurotoxin to infants, further study of its pharmacodynamics is warranted.

Comment in

Mercury, infant neurodevelopment, and vaccination. [J Pediatr. 2000]
Mercury, infant neurodevelopment, and vaccination.Pless R, Risher JF. J Pediatr. 2000 May; 136(5):571-3.

PMID:: 10802503; [PubMed - indexed for MEDLINE]

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