Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
RNA. 2000 Apr;6(4):485-98.

The scene of a frozen accident.

Author information

  • 1Department of Chemistry and Biochemistry, University of Texas at Austin, 78712, USA. andy.ellington@mail.utexas.edu

Abstract

It has been suggested that in vitro selection experiments can provide information not only on what might have occurred during the evolution of the RNA world, but can in fact yield insights into particular features of the RNA world. In particular, it has been suggested that the sequences of anti-amino acid aptamers can provide clues to the origin of the genetic code, and that there is a statistically significant association between motifs found in aptamers and codons. We argue that the suggested connections between modern motifs and ancient sequences are logically tenuous, and show that there is no statistically meaningful association between motifs found in aptamers and codons.

PMID:
10786840
[PubMed - indexed for MEDLINE]
PMCID:
PMC1369930
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Write to the Help Desk