Trends Biochem Sci. 2000 May;25(5):229-35.

Phosphoinositide signaling and the regulation of membrane trafficking in yeast.

Source

Dept of Cellular and Molecular Medicine and Howard Hughes Medical Institute, University of California, San Diego, La Jolla, CA 92093-0668, USA.

Abstract

Phosphoinositides are key regulators of diverse cellular processes in eukaryotic cells. Genetic studies in yeast have advanced our understanding of how phosphoinositide-signaling pathways regulate membrane trafficking. Enzymes required for the synthesis (kinases) and turnover (phosphatases) of distinct phosphoinositides have been identified and several downstream effector molecules linked to phosphoinositide signaling have recently been characterized.

PMID:: 10782093; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Review

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Molecular Biology Databases

Saccharomyces Genome Database

Supplemental Content

Related citations

Review Phosphoinositide kinases. [Annu Rev Biochem. 1998]
Review Phosphoinositide kinases.
Fruman DA, Meyers RE, Cantley LC. Annu Rev Biochem. 1998; 67:481-507.
Review Pathways for phosphoinositide synthesis. [Chem Phys Lipids. 1999]
Review Pathways for phosphoinositide synthesis.
Tolias KF, Cantley LC. Chem Phys Lipids. 1999 Apr; 98(1-2):69-77.
The p21-activated protein kinase-related kinase Cla4 is a coincidence detector of signaling by Cdc42 and phosphatidylinositol 4-phosphate. [J Biol Chem. 2004]
The p21-activated protein kinase-related kinase Cla4 is a coincidence detector of signaling by Cdc42 and phosphatidylinositol 4-phosphate.
Wild AC, Yu JW, Lemmon MA, Blumer KJ. J Biol Chem. 2004 Apr 23; 279(17):17101-10. Epub 2004 Feb 6.
Review Phosphatidylinositol 3-kinase. [Bioessays. 1994]
Review Phosphatidylinositol 3-kinase.
Kapeller R, Cantley LC. Bioessays. 1994 Aug; 16(8):565-76.
Review Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae. [Biochim Biophys Acta. 2007]
Review Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae.
Strahl T, Thorner J. Biochim Biophys Acta. 2007 Mar; 1771(3):353-404. Epub 2007 Feb 6.

See reviews... See all...

Cited by 63 PubMed Central articles

Phosphatidylinositol 3-monophosphate is involved in toxoplasma apicoplast biogenesis. [PLoS Pathog. 2011]
Phosphatidylinositol 3-monophosphate is involved in toxoplasma apicoplast biogenesis.
Tawk L, Dubremetz JF, Montcourrier P, Chicanne G, Merezegue F, Richard V, Payrastre B, Meissner M, Vial HJ, Roy C, et al. PLoS Pathog. 2011 Feb; 7(2):e1001286. Epub 2011 Feb 17.
Sphingosine kinases and their metabolites modulate endolysosomal trafficking in photoreceptors. [J Cell Biol. 2011]
Sphingosine kinases and their metabolites modulate endolysosomal trafficking in photoreceptors.
Yonamine I, Bamba T, Nirala NK, Jesmin N, Kosakowska-Cholody T, Nagashima K, Fukusaki E, Acharya JK, Acharya U. J Cell Biol. 2011 Feb 21; 192(4):557-67. Epub 2011 Feb 14.
Review PI3Kinase signaling in glioblastoma. [J Neurooncol. 2011]
Review PI3Kinase signaling in glioblastoma.
Lino MM, Merlo A. J Neurooncol. 2011 Jul; 103(3):417-27. Epub 2010 Nov 10.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
OMIM (calculated)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as references in the light bulb links within or in the citations at the end of the OMIM record. The references available through the light bulb link are collected using the PubMed related articles algorithm to identify records with similar terminology to the OMIM record.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Domains
Conserved Domain Database (CDD) records that cite the current articles. Citations are from the CDD source database records (PFAM, SMART).
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Phosphoinositide signaling and the regulation of membrane trafficking in yeast.
Phosphoinositide signaling and the regulation of membrane trafficking in yeast.
Trends Biochem Sci. 2000 May ;25(5):229-35.

PubMed
Emerging methods in comparative effectiveness and safety: symposium overview and...
Emerging methods in comparative effectiveness and safety: symposium overview and summary.
Med Care. 2007 Oct ;45(10 Supl 2):S5-8.

PubMed
Aerosolized antibiotics and ventilator-associated tracheobronchitis in the inten...
Aerosolized antibiotics and ventilator-associated tracheobronchitis in the intensive care unit.
Crit Care Med. 2008 Jul ;36(7):2008-13.

PubMed
SRC mediates a switch from microtubule- to actin-based motility of vaccinia viru...
SRC mediates a switch from microtubule- to actin-based motility of vaccinia virus.
Science. 2004 Oct 1 ;306(5693):124-9. Epub 2004 Aug 5 .

PubMed
Dipeptidyl peptidase-4 inhibitors and the management of type 2 diabetes mellitus...
Dipeptidyl peptidase-4 inhibitors and the management of type 2 diabetes mellitus.
Curr Opin Endocrinol Diabetes Obes. 2007 Apr ;14(2):98-107.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to: