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J Bacteriol. 2000 May;182(10):2989-91.

Control of initiation of sporulation by replication initiation genes in Bacillus subtilis.

Author information

  • 1Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

Abstract

Initiation of spore formation in Bacillus subtilis appears to depend on initiation of DNA replication. This regulation was first identified using a temperature-sensitive mutation in dnaB. We found that mutations in the replication initiation genes dnaA and dnaD also inhibit sporulation, indicating that inhibition of sporulation is triggered by general defects in the function of replication initiation proteins.

PMID:
10781575
[PubMed - indexed for MEDLINE]
PMCID:
PMC102015
Free PMC Article

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