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    Genome Res. 2000 Apr;10(4):539-42.

    Promoter prediction on a genomic scale--the Adh experience.

    Ohler U.

    Lehrstuhl für Mustererkennung, University of Erlangen-Nuremberg, D-91058 Erlangen, Germany. ohler@informatik.uni-erlangen.de

    We describe our statistical system for promoter recognition in genomic DNA with which we took part in the Genome Annotation Assessment Project (GASP1). We applied two versions of the system: the first uses a region-based approach toward transcription start site identification, namely, interpolated Markov chains; the second was a hybrid approach combining regions and signals within a stochastic segment model. We compare the results of both versions with each other and examine how well the application on a genomic scale compares with the results we previously obtained on smaller data sets.

    PMID: 10779494 [PubMed - indexed for MEDLINE]

    PMCID: 310866

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