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Chem Biol. 2000 Apr;7(4):R85-94.

Antagonists of protein-protein interactions.

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  • 1Department of Protein Engineering, Genentech, Inc., South San Francisco, CA 94080, USA. andrea@gene.com

Abstract

Protein-protein interactions are often attractive, but not straightforward, targets for disease therapy. Two strategies for identifying inhibitors of these interactions, peptide phage display and high-throughput screening, have recently shown new promise.

PMID:
10779412
[PubMed - indexed for MEDLINE]
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